Shared teaching with multimedia‐enhanced video‐conferencing

Video‐conferencing was used to share a short series of lectures between several universities. A high bandwidth network (155Mbit/s) permitted near broadcast TV quality video to be combined with fully mixed, high‐quality audio. The lectures were supported by visual aids made available using Microsoft NetMeeting to provide multipoint, shared applications. NetMeeting is shown to be a stable and effective platform for distributing multimedia material at a much higher resolution than is possible using the video signals common in most video‐conference lectures, although care must be taken when constructing animated material

Implementing a Bottom of the Pyramid Eye Care Solution

Eighty-nine percent of the world’s visually impaired live in low-income regions (IAPB/WHO), and uncorrected refractive errors are the main cause of moderate and severe visual impairment. Poor eye care in developing nations hinders development and advancement by creating barriers to education and labor inefficiencies. In some developing countries, few individuals can afford, or even have access to, corrective eye care. We propose the global eye care problem can be addressed using bottom of the pyramid thinking

Apps, Agents, and Improvisation: Ensemble Interaction with Touch-Screen Digital Musical Instruments

This thesis concerns the making and performing of music with new digital musical instruments (DMIs) designed for ensemble performance. While computer music has advanced to the point where a huge variety of digital instruments are common in educational, recreational, and professional music-making, these instruments rarely seek to enhance the ensemble context in which they are used. Interaction models that map individual gestures to sound have been previously studied, but the interactions of ensembles within these models are not well understood. In this research, new ensemble-focussed instruments have been designed and deployed in an ongoing artistic practice. These instruments have also been evaluated to find out whether, and if so how, they affect the ensembles and music that is made with them. Throughout this thesis, six ensemble-focussed DMIs are introduced for mobile touch-screen computers. A series of improvised rehearsals and performances leads to the identification of a vocabulary of continuous performative touch-gestures and a system for tracking these collaborative performances in real time using tools from machine learning. The tracking system is posed as an intelligent agent that can continually analyse the gestural states of performers, and trigger a response in the performers' user interfaces at appropriate moments. The hypothesis is that the agent interaction and UI response can enhance improvised performances, allowing performers to better explore creative interactions with each other, produce better music, and have a more enjoyable experience. Two formal studies are described where participants rate their perceptions of improvised performances with a variety of designs for agent-app interaction. The first, with three expert performers, informed refinements for a set of apps. The most successful interface was redesigned and investigated further in a second study with 16 non-expert participants. In the final interface, each performer freely improvised with a limited number of notes; at moments of peak gestural change, the agent presented users with the opportunity to try different notes. This interface is shown to produce performances that are longer, as well as demonstrate improved perceptions of musical structure, group interaction, enjoyment and overall quality. Overall, this research examined ensemble DMI performance in unprecedented scope and detail, with more than 150 interaction sessions recorded. Informed by the results of lab and field studies using quantitative and qualitative methods, four generations of ensemble-focussed interface have been developed and refined. The results of the most recent studies assure us that the intelligent agent interaction does enhance improvised performances

Cryptococcus neoformans Antigenemia in HIV Positive Pregnant Women Attending a PMTCT Clinic in South-East Nigeria

Cryptoccocus neoformans infection is life threatening especially when associated with HIV disease. Unfortunately, in our environment, scant attention has been paid to screening for this fungal disease despite reports of relatively high co-infection rates with HIV in other countries facing similar HIV/AIDS burden. Among people living with HIV/AIDS, there is a significant population of pregnant women. In pregnancy itself, there is immunosuppression, thus combining with the immunosuppression seen in HIV disease. This study was therefore designed to determine the prevalence of cryptoccocus neoformans infection, among HIV seropositive pregnant women attending a prevention of mother to child transmission (PMTCT) of HIV treatment centre. Two hundred and eighty (280) women were recruited for the study. One hundred and sixty (160) of the subjects were HIV seropositive (test group) while 120 HIV seronegative pregnant women served as controls. The test group was sub-divided into three groups based on their CD4 counts: <200, 200-300 and >300 cells??l. Blood was collected by venipuncture and HIV status was determined by current national serial algorithm using Determine and Stat Pak test kits. The test for Cryptoccocus neoformans was performed using latex cryptococcal antigen (CRAG) detection kits.CD4 counts was determined using the Partec cyflow analyzer.  A prevalence rate of 13.1% was observed among HIV seropositive subjects, while none (0%) of the control group tested positive. Cryptococcal antigenemia correlated with decreasing CD4 counts with most of the positive subjects having CD4 counts below 200 cells/?l. It is recommended that targeted cryptococcal screening be made a part of baseline tests in HIV positive pregnant women with low CD4 + T cell counts. This will reduce preventable deaths and improve obstetric outcome in this vulnerable group. Keywords: Cryptoccocus neoformans, HIV/AIDS, Pregnanc

Future Contingents and the Logic of Temporal Omniscience

At least since Aristotle’s famous 'sea-battle' passages in On Interpretation 9, some substantial minority of philosophers has been attracted to the doctrine of the open future--the doctrine that future contingent statements are not true. But, prima facie, such views seem inconsistent with the following intuition: if something has happened, then (looking back) it was the case that it would happen. How can it be that, looking forwards, it isn’t true that there will be a sea battle, while also being true that, looking backwards, it was the case that there would be a sea battle? This tension forms, in large part, what might be called the problem of future contingents. A dominant trend in temporal logic and semantic theorizing about future contingents seeks to validate both intuitions. Theorists in this tradition--including some interpretations of Aristotle, but paradigmatically, Thomason (1970), as well as more recent developments in Belnap, et. al (2001) and MacFarlane (2003, 2014)--have argued that the apparent tension between the intuitions is in fact merely apparent. In short, such theorists seek to maintain both of the following two theses: (i) the open future: Future contingents are not true, and (ii) retro-closure: From the fact that something is true, it follows that it was the case that it would be true. It is well-known that reflection on the problem of future contingents has in many ways been inspired by importantly parallel issues regarding divine foreknowledge and indeterminism. In this paper, we take up this perspective, and ask what accepting both the open future and retro-closure predicts about omniscience. When we theorize about a perfect knower, we are theorizing about what an ideal agent ought to believe. Our contention is that there isn’t an acceptable view of ideally rational belief given the assumptions of the open future and retro-closure, and thus this casts doubt on the conjunction of those assumptions

European technical guidance document for the flexible scope accreditation of laboratories quantifying GMOs

The aim of this guidance document is to facilitate harmonised flexible scope accreditation within Europe, according to ISO/IEC 17025:2005 related to quantitative testing of genetically modified organisms (GMOs) by quantitative real-time polymerase chain reaction (qPCR) for GM events authorised in the EU or which are in the authorisation process. This document gives guidance to and is intended for laboratories that are considering to acquire a flexible scope of accreditation according to ISO/IEC 17025. At the same time it aims to provide information for assessors involved in the accreditation process of these laboratories. This guidance document has been written by members of the Task Force (TF) Flexible scope accreditation, which has been initiated by European Commission, Joint Research Centre, Institute for Reference Materials and Measurements (EC JRC-IRMM, Geel, BE). After an extensive commenting phase it has been submitted to the European co-operation for Accreditation (EA) in February 2013 for consideration as an EA guidance document.JRC.D.2-Standards for Innovation and sustainable Developmen

A NEWLY FORMING COLD FLOW PROTOGALACTIC DISK, A SIGNATURE of COLD ACCRETION from the COSMIC WEB

How galaxies form from, and are fueled by, gas from the intergalactic medium (IGM) remains one of the major unsolved problems in galaxy formation. While the classical Cold Dark Matter paradigm posits galaxies forming from cooling virialized gas, recent theory and numerical simulations have highlighted the importance of cold accretion flows - relatively cool (T ∼ few × 104 K) unshocked gas streaming along filaments into dark matter halos, including hot, massive, high-redshift halos. These flows are thought to deposit gas and angular momentum into the circumgalactic medium resulting in disk- or ring-like structures, eventually coalescing into galaxies forming at filamentary intersections. We earlier reported a bright, Lyα emitting filament near the QSO HS1549+19 at redshift z = 2.843 discovered with the Palomar Cosmic Web Imager. We now report that the bright part of this filament is an enormous (R > 100 kpc) rotating structure of hydrogen gas with a disk-like velocity profile consistent with a 4 × 1012 M o halo. The orbital time of the outer part of the what we term a "protodisk" is comparable to the virialization time and the age of the universe at this redshift. We propose that this protodisk can only have recently formed from cold gas flowing directly from the cosmic we